Iowa State has won the last two games in this series, but K-State won eight out of the last 11 meetings between these two. The Wolverines have to get past Indiana first on Saturday. This week will show just how good the SEC is, and just how underrated the Big 12 is, with incredible conference games on deck. Vegas: Florida -11.5. 21+ (18+ NH/WY). Texas A&M hasn't won a game since the end of September and Florida is on a two-game losing streak. ET: The latest in the sports world, emailed daily. Predictions for each Week 6 game are broken into three sections: Top 25 teams, best games between unranked teams and the rest of the slate. 14 Illinois, 3:30 p.m. The Demon Deacons are coming off of a 31-21 road win over a much improved Florida State team. Ole Miss has won the last three straight over Vanderbilt. In four games against FBS opponents, Syracuse has thrown for a total of 510 yards and one touchdown. No. Undefeated Tennessee comes into this one boasting one of the country's most explosive offenses. The latest in the sports world, emailed daily. ET, ESPN3), No. ET, Pac-12 Network), Florida State at No. Michigan has held all five of its opponents to 17 points or fewer, but we're also talking about five offenses that rank outside of the top 60 in the country in total yards per game. The Crimson Tide know that it's time to hit the gas if they want to be playing for the national championship. This should also give the ACC's rushing leader, running back Sean Tucker, time to rest uphe got banged up during Syracuse's blowout win over Wagner. CFB PICKS. They allow two more points and 14 more total yards per game. QB Jaxson Dart has thrown for 910 yards and five touchdowns on the year. Bearcat quarterback Ben Bryant, who had to replace longtime starter Desmond Ridder this season, has Cincy's offense running smoothly. . 17 Ole Miss (3-1) vs. No. In the exception to that rule, though, Texas scored 70 and ran all over the Red Raiders, so it wouldn't be much of a surprise if Zach Evans has a field day for TCU. 2021 Week 6 Matchups. Enjoy the free college football picks against the spread as well! ET: Houston 32, SMU 26, Auburn at Mississippi State, 7:30 p.m. Top college football predictions for Week 3. Florida has won 29 of the last 30 games in this series, including a 56-0 victory two years ago. No. ET: Washington State 23, Stanford 17, West Virginia at Iowa State, 3:30 p.m. The Tigers are more vulnerable to an upset than their Top Five ranking would seem. I think this one will be close for awhile before Tennessee pulls away in the fourth. The most surprising team in college football gets its time in the spotlight on Saturday. Nick Saban told reporters earlier this week that Young is "day-to-day.". Week 6 doesn't feature a ton of big games, but there are a number of fun matchups on the slate. It looks like they'll keep a position there since they're playing a Memphis team that's on a three-game losing streak, had a 1-4 record in October and has fielded one of the worst defenses in the AAC. Michigan has a new look and confidence to them behind quarterback J.J. McCarthy. The Ducks will head to Buffaloes territory and pummel Colorado on the road. There aren't a lot of big-time matchups, but some wild ones are upcoming. Head coach Brian Kelly and the Tigers started the season slow with a loss in Week 1, but it's been mostly positive from there. Select A Week 6 Matchup: Thursday, October 7th - Houston Vs Tulane. 5 Clemson at Boston College, 7:30 p.m. These are two programs on completely opposite paths. Michigan has impressed the last two weeks, defeating Maryland and beating Iowa on the road handily 27-14. Still, a fight for the top four will get even tougher in the next few weeks. Rock chalk! 10 UCLA at Arizona State, 9:30 p.m. The Buckeyes need to be dominant in this matchup to continue to show the selection committee just how good they are, and they'll be exactly that. No. ET kickoff . It was 45-3 in the fourth quarter before the Broncos padded their stats a bit with a couple of long touchdown passes, but it was a beatdown in Idaho against a ranked Boise State team. ET, Pac-12 Network), No. Predicting NFL Week 6 upsets, plus weekly buzz, notes Geno Smith's stock is pointing up, while Russell Wilson's play as a Bronco has been subject to critique. ET: UTSA 26, UAB 19, Navy at Cincinnati, 4 p.m. Heading into Week 6 of the college football season, we've yet to see too many upsets come from the nation's top five teams. I put this one out at -3, but would play it to -4.5. ET on ESPNU, live stream on fuboTV (Start your free trial)Missouri gave Georgia a serious scare last week, leading the Bulldogs for most of that game. It doesn't seem like Brown shows many elusive moves on the field compared to backs across the country, but he carries the ball more than most. Saturday's game against Utah will prove if this UCLA team is for real or not. Kansas will play host to College GameDay for the first time in program history as it attempts to go to 6-0 with a win over TCU. The Horned Frogs can afford a high concession or two because their offense is averaging 549.5 total yards per game, which is 129 yards above Kansas' average. Tennessee's tempo will likely wear down this LSU frontthe Vols like to go fast, which can make even the stingiest defenses tired. He's rushed for another 329 yards and five touchdowns, too. ET: Louisiana 27, Troy 19, Texas State at Louisiana Monroe, 5 p.m. The normally high-octane offense of Ole Miss was flummoxed by Alabama. ET: Hawai'i at San Diego State, 10:30 p.m. The former 4-star recruit from the class of 2018 started his career at Michigan. The Rebels will score a few times. 7 in the AP poll for that one, but they were down 24-0 in the blink of an eye. The Aggies were one of just two teams to beat Alabama last season, upsetting the Tide 41-38 at home. ET, ESPN) Florida . 2 Georgia (5-0), 3:30 p.m. Arizona State hasn't been terrible, with a 3-5 overall record, but it is unlikely to stop UCLA's offense. This would've been a more favorable matchup for ND if the Tigers didn't have two weeks to get back to the drawing board. 10 Penn State eked out a 17-12 victory over No. Multiple teams from the conference are in the running for the top four after the initial CFP rankings release, as are usual challengers Ohio State, Clemson and Michigan. 9 Michigan (5-0) at Nebraska (3-3), 7:30 p.m. 17 Ole Miss covers as a six-point favorite against No. 2 Tennessee. Arizona State is back in the AP Top 25 after a 42-23 road win over then-No. Truly, it wouldn't be a surprise if Coastal Carolina scores on every possession. The Golden Bears will make that five straight losses. The Eagles have struggled so far this season, losing to Rutgers to open the year before dropping two out of its last four against Virginia Tech and Florida State. 19 Kansas (noon ET, FS1), Arkansas at No. They'll have this week off to prepare for back-to-back road games against Boston College and Miami. The Blue Devils are 4-1 on the season, losing to Kansas in Week 4. Saturday will mark just the fourth overall meeting between these two. After losing to an unranked Stanford team that didn't even jump into the AP Top 25 as a result of the upset, Oregon didn't fall as far as expected (from No. It's been an up-and-down road for the Tigers, but they've had back-to-back weeks scoring more than 40 points against SEC opponents. He has added another 255 yards and three scores on the ground, too. The Longhorns were on a bye week last weekend, which came at a great time as they try to make a late-season push. The 'Noles run game features Treshaun Ward and Trey Benson, who have combined for 715 yards and six touchdowns on the ground. 20 Kansas State at Iowa State, 7:30 p.m. The 6-2 UCF Knights are in the AP Top 25 for the first time in the Gus Malzahn era. 21 Washington at Arizona State. They'll be back next Friday for a home game against 1-4 California, which should be an easy victory. Since his firing, the Sun Devils are 0-2 with losses to Utah and USC. 20 UCLA, and Stanford certainly shook up the rankings with its 31-24 victory over then-No. Army, meanwhile, has struggled consistently so far this season. ET. . This won't be a close one, at all. If that mutual recent trend continues, there could be a major upset brewing in Lincoln. Prediction: Air Force 31, Wyoming 20, Third-Best: TCU (2-2) at Texas Tech (4-1), 7 p.m. Based on 1000s of simulations, our computer analyzes the data for each and every College Football game to provide the best College Football picks and odds for you to . Last year, Oklahoma came from behind from a 28-7 first-quarter deficit to win 55-48 in a thriller. But even if LSU's defense can hold up well, I'm not sure LSU has the firepower to keep pace with a high-scoring Vols offense. Georgia Tech (2-3) at Duke (3-2), 12:30 p.m. It's a bit surprising, given this Sparty team won the Peach Bowl last season. It is allowing just 8.9 points and 75.6 yards on the ground. I suspect quarterback Tanner Mordecai and Co. will have enough firepower to get this W. But it's going to come right down to the wire. The weekend boasts a quartet of Top 25 showdowns, including a . He played in 13 games over three . ET. But that ship sailed last Saturday, so Mississippi State might have more motivation entering this one. I like Oklahoma State at home here. 21 Texas, and No. Lower stakes bring out the worst in the Bulldogs, who have covered one of their past six games . Notre Dame has back-to-back wins, defeating Syracuse and UNLV. Take a page from Missouri's playbook, dial up (at least) 52 passes and hope Max Johnson has a similar 4-1 TD-to-INT ratio. Kansas should have one of the best crowds in program history behind the team on Saturday, and it gained some experience playing in close games to start the season. Accountability Time: After a terrible 10-21 showing against the spread in Week 4, we rallied with a 16-11 record this past week, including correctly projecting the outright upsets by Arizona State, Michigan and Mississippi State. Taulia Tagovailoa, the younger brother of Miami Dolphins QB Tua Tagovailoa, has had a decent season. ET: TCU's defense has allowed at least 32 points and more than 400 yards of total offense in three consecutive games against Cal, SMU and Texas. Penn State has lost two of its last three games, which is discouraging, but the recent competition has been fierce. One of the most explosive teams in the nation is headed to Athens to face the defending champion Georgia Bulldogs. 3 to No. Fighting Irish running back Audric Estime has rushed for 210 yards and three touchdowns in the last two weeks. Let's get back on the right track. Three games between ranked teams, including No. Longhorns QB Quinn Ewers was injured in the first quarter against Alabama on Sept. 10, and he hasn't seen the field since. Prediction: Ohio State 56, Michigan State 13. 21 . The 2022 College Football Week 6 will feature Tennessee Vs LSU and Texas Tech Vs Oklahoma St. We will have 6 more Premium Picks against the spread this week! Clemson has had two close bouts against Syracuse and Florida State in their last two games. And it definitely feels like they have no hope of keeping pace with an Alabama team that has now scored at least 31 points in 31 consecutive games. TCU's Max Duggan has yet to throw an interception this season, and he had three touchdown passes in the last two weeks. In the last three weeks, CJ Stroud and the Buckeyes' offense have put up an average of 59 points. Arizona's poor defense that gives up 475 yards per game won't be able to stop the Utes. Texas Tech's defense is allowing 27.6 yards per game. The Trojans are averaging 307.9 yards in the air, with Williams recording 24 touchdowns and only one interception. 17 Iowa. The Huskies are 14-point favorites over the Sun Devils. Maye is tied at No. At the beginning of the season, this one looked like it could have major playoff implications. 14 Ole Miss (-6.5). In the last three weeks, he's combined for seven passing touchdowns and five scores on the ground. No. Florida (vs. Missouri) 12 p.m. ET: Nebraska 28, Rutgers 17, Houston at Memphis 7:30 p.m. ET . No. Tech's defense forced two turnovers that set up a pair of scores. The Razorbacks had a chance to defeat TAMU, but doinked a game-winning field goal attempt off the top of the upright. Although Kentucky quarterback Will Levis fumbled twice late in the game against Ole Miss to give the Rebels the victory, I think he will rebound nicely against South Carolina. It's unclear if either QB will suit up Saturday. Here are five questions that need to be answered this week and our Week 6 predictions. Georgia will take down the Volunteers to give them their first loss since last season. Of particular note in advance of this showdown with Michigan, Nebraska has allowed just three rushing touchdowns all season and has limited its two most recent Big Ten foes to 56 carries for 108 yards. This one should be close throughout, and the Bruins might have a slight advantage in taking this one at home. Both Air Force and Army can light up the scoreboard, mostly using a rushing attack. But what he did against LSUrepeatedly running around like a chicken with its head off before pulling some magical play out of nowherealmost certainly isn't going to fly against this Georgia defense. ET: This one is compelling because it's a chance for Oregon State to become an AP Top 25 team for the first time in more than eight years. Freshman running back Quinshon Judkins has been sensational this season, accounting for 535 yards and six touchdowns so far. But if that's the case, advantage Virginia Tech, which has the more mobile of the two quarterbacks. 17 TCU . North Carolina beat Virginia Tech 41-10 last week, whereas Miami has yet to begin conference play. The Cougars are averaging just 29.6 points per game, compared to USC's 10th ranked scoring offense (42 PPG). Kansas will play host to College GameDay for the first time in program history as it attempts to go to 6-0 . Last week, the Tigers' defense forced four turnovers against Auburn to come from down 17 points to win 21-17. ET, Florida Atlantic (3-2) at UAB (3-2), 3:30 p.m. 118: Eastern Michigan Eagles 24.7. Kansas' Jalon Daniels has thrown for 983 yards, 11 touchdowns and just one interception. They needed to make a winning impact, and although the month of October was a difficult stretch for the Noles (1-3 record), they appear to be on the right path. That could make all the difference in covering the 6.5 points if they do not come out on top. ET: San Jos State 17, Colorado State 10, Hawai'i at Fresno State, 10:30 p.m. Unfortunately, quarterback Spencer Sanders has been digressing each week throughout the season so far. Penn State won't be a riser after a win against Indiana, unless it demolishes the Hoosiers on the road. All Top 25 games Saturday unless otherwise noted. Premium Picks are made public once the games are played. And goodness knows Oklahoma has had a propensity for nail-biters this season. Texas and Oklahoma are afterthoughts in the Big 12 title race right now. ET. 15 Coastal Carolina (5-0) at Arkansas State (1-4), 7:30 p.m. 3 Iowa (5-0), 4 p.m. Without fail, there's one game every week in these predictions that I just stare at for 10-15 minutes before accepting that I have no clue what to expect. 17 Ole Miss. The Panthers were another team with high expectations heading into the season, but transfer QB Kedon Slovis and Co. have sputtered to 4-4. At long last, we've reached the #Pac12AfterDark on a Friday night portion of the regular season, and what a fantastic game to get that party started. 24 Cincinnati vs. South Florida , 2:30 p.m. That could give the Jayhawks an edge in this one. College football's Week 8 slate for the 2022 season features 54 games, and our NCAA experts are ready with their predictions and picks. Predictions for each Week 6 game are broken into three sections: Top 25 teams, best games between unranked teams and the rest of the slate. 13 Arkansas (4-1), Noon ET, No. Vanderbilt's defense checks in at 114th in scoring defense nationally. Unless otherwise noted, games are assumed to take place on Saturday. No. Prediction: Utah 28, USC 27, Sicko Special: Connecticut (0-6) at Massachusetts (0-5), 3:30 p.m. In fact, the Hogs' last four opponents have been held without a single passing touchdown and limited to 105.5 passing yards on average. Oklahoma State is fifth in scoring offense, averaging 47.8 points per game. ET: Coastal Carolina at UL Monroe, 8 p.m. Arkansas has lost its last two games to Texas A&M and Alabama. 3 Iowa. The Hawkeyes will be the beneficiary of a game-changing swing midway through the fourth quarter to keep the dream of a perfect season intact. . Vanderbilt (+38.5) over GEORGIA. 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